A case-control study of 25-hydroxyvitamin D deficiency in psoriasis patients

Introduction: Reduced vitamin D levels are found in some autoimmune diseases like rheumatoid arthritis, multiple sclerosis and more recently psoriasis. Objective: This study was conducted to analyze vitamin D status of psoriasis patients in comparison to healthy controls. Materials and Methods: This prospective case control study was conducted on 100 patients (50 with psoriasis and 50 age and sex matched controls) from the outpatient clinic of our dermatology department. Results: Vitamin D levels were significantly lower in psoriasis patients compared with controls. Deficiency (<20 ng/mL) was seen in 96% psoriasis patients and 64% controls. (P value <0.0001) while the prevalence of insufficiency (<30 ng/mL) was 100% in psoriasis group compared with 80% in control group. Conclusion: Vitamin D levels are significantly low in psoriasis patients as compared to control group.